Adrenaline spike meaning11/24/2023 We will talk more below about this below in terms of two important examples: From our point of view the difference between 4 degrees and room temperature where drugs are stored is minimal Upon freezing, the density of water decreases by about 9% (If this was not the case the world would be a much different place where Ice would sink in your drink and to the bottom of the ocean). ** Why 4 degrees? – Water is at its ‘most dense’ at 4 Degrees Celsius. This solution would have 1g per 100mls:.These Solutions have 100g of drug in 100mls of Fluid Therefore, as far as medications are concerned a 1 in 1 (1 gram per 1ml) Solution is the same as a 100% Solution.It means that 100mls of Water has a weight of 100g (at 4 Degrees Celsius**).įrom this we can say that a 100% solution would be 1 gram of drug in 1ml of volume In this post we make a Basic Assumption for the properties of fluids using water at 4 degrees celsius as an example (shown in the blue picture below).Using weight of a chemical or drug can be confusing when we are dealing with medications that are diluted because diluted drugs have different concentrations.If you recall back to school, in chemistry class ‘weights’ rather than ‘volumes’ are often used in reference to chemical substances.Paediatric Entertainment Solution (“P.E.S.”) (1:1000 dilution or 0.1%) The Boring Bit just 2 minutes (promise) of back to school chemistry: It is critical to know Drug Dilution by heart for drugs such as Adrenaline (Epinephrine).It is easy to confuse when rushing or in an emergency.We set out a helpful introduction for average people like us to the supposedly simple yet confusing concepts. There is a particular focus on adrenaline (epinephrine). In this post we would like to talk about drug dilutions for injectable medications. In healthcare the classic confusion exists with “%” solutions and “1:1000” dilutions. Well, don’t worry if you are not sure, panic is most people’s initial thought. When put on the spot can you tell ‘ how many milligrams of Lignocaine (lidocaine) there are in 5mls of a 1 percent solution?‘
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